The Blood of Dawnwalker offers four difficulty presets:
| Preset | Notes |
|---|---|
| Story | |
| Fair | |
| Challenging | |
| Duelist | Removes directional attack indicators; enemies have less health but hit harder; Coen has very little stamina. |
- RPG Difficulty and Action Difficulty can be tuned independently of the preset.
- Difficulty can be changed mid-run.